Transcranial alternating current stimulation and its influences on neurophysiological mechanisms of error processing and error regulation in healthy subjects and patients with attention deficit hyperactivity disorder (ADHD)
- Conditions
- Healthy SubjectsF90.0Disturbance of activity and attention
- Registration Number
- DRKS00008209
- Lead Sponsor
- Institut für Medizinische Psychologie und Medizinische SoziologieUniversitätsklinikum Schleswig-Holstein
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 50
• consent of subjects and their parents • Age 10 - 30 years • Male • right handed.
For patients: ICD-10(F90.0)
• internal , neurological and other psychiatric disorders
• IQ < 85
• medication
• Conduct disorder
• seizures ( epilepsy ) , seizures ( even once) , febrile convulsions , increased excitability of the brain ( a history of : epilepsy typical potentials or other patho - logical EEG changes )
• metal implants in the head area ( inserted into the header area metal ) : for example, In - plantation of artificial cochlea ( cochlear )
• condition after head injury with loss of consciousness
• Any pre-existing condition of the heart pacemaker
• Lack of Compliance
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method On the behavioural level, reaction time, its variability, omission and commission errors will be analysed;<br>Error related negativity and positivity;<br>Power of theta and alpha; <br>On the source level, the harmonic frequency will be analyse using Dynamic Imaging of Coherent Sources. <br>These parameters are recorded for each stimulation condition.
- Secondary Outcome Measures
Name Time Method Adverse events questionnaire (1).<br>Wenn: After each experimental session.<br><br>(1) C. Poreisz, K. Boros, A. Antal, W. Paulus, Safety aspects of transcranial direct current stimulation concerning healthy subjects and patients, Brain Res Bull, 72 (2007) 208-214
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