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临床试验/NCT05669131
NCT05669131尚未招募不适用

Motor Imagery Training, Force Steadiness and Neural Drive

University of British Columbia0 个研究点目标入组 60 人开始时间: 2022年12月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
60
主要终点
Force steadiness

研究概览

简要总结

The goal of this clinical trial is learn about motor imagery training (i.e. imagining a task) with healthy older adults. The main question this clinical trial aims to answer is:

• Will imagining a task improve control of force during an elbow flexion muscle contraction in healthy older adults?

Participants will:

  • Complete questionaries about general activity levels and ability to imagine tasks
  • Perform either motor imagery training or watch a documentary
  • Perform maximal and submaximal elbow flexion contractions

Researchers will compare the motor imagery training with the control group to see if control of force is improved in the motor imagery training group.

详细描述

Motor imagery training could be beneficial in rehabilitative settings when participants are not physically capable of preforming a motor task or in injury prevention scenarios such as when multiple repetitions of a motor task should not be performed. If the effects of motor imagery training are favourable then they could have meaningful influence on the performance of steady movements in older adults who experience declines in force steadiness with age. Therefore, the first aim of this study will be to determine if one session of motor imagery training will influence corticospinal excitability in older adults and improve force steadiness during isometric elbow flexion contractions with the observed benefit being greater in females. The second aim of this study will be to determine if there is an associated change in oscillations in common synaptic input to motor neurons with a change in force steadiness.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
65 Years 至 90 Years(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy older adults aged 65 to 90 years old

排除标准

  • have had an injury or orthopaedic surgery to the arm or shoulder in the prior 6 months
  • are involved in high levels of upper-body strength training
  • have history of training in fine motor tasks (i.e., musicians)
  • have a history of MIT
  • have systemic diseases and/or nerve damage affecting neuromuscular function
  • have severe cognitive impairment
  • are unable to read or speak English fluently
  • are left hand dominant

结局指标

主要结局

Force steadiness

时间窗: Within one session: Change from baseline (immediately before session) to 20 minutes after the session

Measured as the the coefficient in variation of force

Corticospinal excitability

时间窗: Within one session: Change from baseline (immediately before session) to 20 minutes after the session

Measured as the peak-to-peak amplitude of a motor evoked potential

Common synaptic input

时间窗: Within one session: Change from baseline (immediately before session) to 20 minutes after the session

Estimated from motor unit discharge times.

次要结局

  • Maximal elbow flexion force(Within one session: Change from baseline (immediately before session) to 20 minutes after the session)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jennifer Jakobi

Professor

University of British Columbia

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