Evaluation of 4D Magnetic Resonance Flow Sequence at Hepatic Level

Not Applicable

Completed

• Conditions: Magnetic Resonance Imaging

• Registration Number: NCT02821078
• Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Brief Summary

The objective of the project is to establish the 3D velocity mapping of the hepatic vasculature and its consistency

Detailed Description

The objective of the project is to establish the 3D velocity mapping of the hepatic vasculature and its consistency. Specifically, the investigators will assess the consistency of the quantitative data by measuring hepatic blood Inflow (hepatic artery + portal vein) and outflow (inferior vena cava differential flow). According to the mass conservation physical property, blood inflow must equals blood outflow. The relative gap between the measured values will characterize the consistency of the acquisition.

Study Timeline

• Study First Submitted: 2016-06-29
• Study First Submitted QC: 2016-06-29
• Study First Posted: 2016-07-01
• Study Start: 2017-03-16
• Primary Completion: 2019-01-24
• Study Completion: 2019-01-24
• Status Verified: 2020-12
• Last Update Submitted: 2020-12-03
• Last Update Posted: 2020-12-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• Participants have fasted for 6 hours before examination
• Adult participants

Exclusion Criteria

• Anyone with a classic contraindication to MRI
• Recanalized umbilical vein
• Severe obesity
• Gadolinium chelate allergy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Hepatic blood flow difference	Day 0	difference between (hepatic artery + portal vein flows) and inferior vena cava differential flow (infra and supra hepatic)

Secondary Outcome Measures

Name	Time	Method
Comparison between 4D and 2D flow	Day 0	Comparison between 4D and 2D flow values measured at the portal trunk level

Trial Locations

Locations (1)

CHU Amiens; 🇫🇷 Amiens, France