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Evaluation of 4D Magnetic Resonance Flow Sequence at Hepatic Level

Not Applicable
Completed
Conditions
Magnetic Resonance Imaging
Interventions
Other: 4D flow imaging sequence
Registration Number
NCT02821078
Lead Sponsor
Centre Hospitalier Universitaire, Amiens
Brief Summary

The objective of the project is to establish the 3D velocity mapping of the hepatic vasculature and its consistency

Detailed Description

The objective of the project is to establish the 3D velocity mapping of the hepatic vasculature and its consistency. Specifically, the investigators will assess the consistency of the quantitative data by measuring hepatic blood Inflow (hepatic artery + portal vein) and outflow (inferior vena cava differential flow). According to the mass conservation physical property, blood inflow must equals blood outflow. The relative gap between the measured values will characterize the consistency of the acquisition.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
44
Inclusion Criteria
  • Participants have fasted for 6 hours before examination
  • Adult participants
Exclusion Criteria
  • Anyone with a classic contraindication to MRI
  • Recanalized umbilical vein
  • Severe obesity
  • Gadolinium chelate allergy

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Participants4D flow imaging sequenceIn addition to the standard clinical MR protocol, 2 added sequences: * 4D flow imaging sequence * standard 2D-PhaseContrast at portal trunk level as reference
Primary Outcome Measures
NameTimeMethod
Hepatic blood flow differenceDay 0

difference between (hepatic artery + portal vein flows) and inferior vena cava differential flow (infra and supra hepatic)

Secondary Outcome Measures
NameTimeMethod
Comparison between 4D and 2D flowDay 0

Comparison between 4D and 2D flow values measured at the portal trunk level

Trial Locations

Locations (1)

CHU Amiens

🇫🇷

Amiens, France

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