Cognitie en het ontwikkelende brein in galactosemie.
Completed
- Conditions
- Classic galactosemia (Klassieke galactosemie)
- Registration Number
- NL-OMON22209
- Lead Sponsor
- Dr. M.E. Rubio-Gozalbo, academisch Ziekenhuis Maastricht
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 52
Inclusion Criteria
For patients, a diagnosis of classic galactosemia as diagnosed by GALT enzyme activity assay or GALT-gene mutation analysis (information obtained from treating physician); Age between 10 and 18 years old.
Exclusion Criteria
Any other disorder or disease that could affect cognitive functioning independently of classic galactosemia (an exception is made for the diagnosis of ADHD, because this disorder is common in this group).
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. The performance on the language-related behavioural paradigms (four paradigms, each focusing on one aspect of speech processing or production);<br /><br>2. The event-related potentials (ERPs) extracted from the EEG recorded during the behavioural tasks and.
- Secondary Outcome Measures
Name Time Method The performance on the neuropsychological test battery (i.e. a composition of tests focusing on the major cognitive domains: memory, attention, speech and language, visuo-motor skills).