Translational research to study the effect and mechanism of microbiota in paediatric immune-mediated diseases.

Completed

• Conditions: immune-mediated diseases / disturbed immune system diseases; 10027665

• Registration Number: NL-OMON30483
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Child
Diagnosed IMD (JCA, IDDM, AD or CD) according to international accepted standards.

Exclusion Criteria

Diseases of the blood or bloodforming organs or the immune system.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Cytokine production profile and character of immune cells of childeren with IMD<br /><br>exposed to several species of microbiota in vitro and in a trans-well system<br /><br>with humane intestinal epithelial cells.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>None</p><br>