Translational research to study the role of regulatory cells in allergy early in life and the induction of regulatory cells in cord blood

Completed

• Conditions: allergy; atopic disease; 10001708

• Registration Number: NL-OMON31515
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

full term newborns
high risk: (inhalation or food) allergic pregnant woman
low risk: (inhalation or food) allergy not present with pregnant woman, nor with the to be father or the to be brothers and sisters (now or earlier in life)

Exclusion Criteria

gebruik van immuun modulerende medicatie tijdens de zwangerschap
roken tijdens de zwangerschap

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main study parameters/endpoints: Cytokine production profile, character of<br /><br>immune cells of full term newborns and functionality of naturally occurring<br /><br>regulatory T cells as well as induced regulatory T cells. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable.</p><br>