A controlled trial of terlipressin plus banding ligation versus terlipressin alone in the management of acute esophageal variceal bleeding

Completed

• Conditions: Acute oesophageal variceal bleeding but stopped bleeding during emergency endoscopy; Nutritional, Metabolic, Endocrine; Oesophageal varices

• Registration Number: ISRCTN28353453
• Lead Sponsor: Republic of China National Science Council (Taiwan)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-03-30
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Cirrhotic patients
2. Acute oesophageal variceal bleeding proven by emergency endoscopy within 12 hours

Exclusion Criteria

1. Association with advanced hepatocellular carcinoma (HCC)
2. Association with other severe systemic illness
3. Association with gastric variceal bleeding
4. Previous shunt operation, endoscopic variceal ligation (EVL), beta-blocker or isosorbide mononitrate (ISMN) within one month
5. Serum bilirubin >10 mg/dl, creatinine >3 mg/dl
6. Presence of encephalopathy >grade 2
6. History of coronary artery disease
7. Uncooperative

Study & Design

• Study Type: Interventional
• Study Design: Not specified