Using Thoracic Electrical Bioimpedance to Measure Stroke Volume and Cardiac Output in Patients Under Spinal Anesthesia for Cesarean Section
试验速览
- 阶段
- 4 期
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Maximum percentage changes in mean blood pressure after spinal anesthesia
研究概览
简要总结
The investigators hypothesize that continuously measuring stroke volume (SV) and cardiac output (CO) will 1) reveal hemodynamic instability in a timely manner and alert the physician promptly, 2) provide information for the physician to make the differential diagnosis as to whether the hemodynamic instability was due to vasodilatation or reduction of venous blood return, and 3) lead to appropriate and prompt treatment to improve patient outcome.
-determine the SV and CO and their kinetic change using ICON® to establish a hemodynamic profile of the patient under spinal anesthesia for cesarean section. To determine if using instantaneous measurements of SV and CO to guide patient management improves hemodynamic stability.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •age 18-45;
- •receiving spinal anesthesia or combined spinal and epidural anesthesia to undergo cesarean section
排除标准
- •Patients who have major cardiovascular disease,preexisting of hypertension or gestational hypertension, preeclampsia and body mass index greater than 35kg/m2;
- •Patients who have skin lesion at the place where the electrode is supposed to be applied;
- •Emergency cesarean section patients.
结局指标
主要结局
Maximum percentage changes in mean blood pressure after spinal anesthesia
时间窗: baseline before spinal anesthesia and up to 20 minutes after spinal anesthesia
次要结局
未报告次要终点
研究者
Yandong Jiang
Assistant professor
Massachusetts General Hospital
