:NCPAP versus HHFNC in treatment of premature infants with respiratory distress

Phase 2

Conditions: respiratory distress syndrome in premature infants.
Respiratory distress syndrome of newborn
P22.0

Registration Number: IRCT20151122025184N2

Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 54

Inclusion Criteria

premature infants with GA fewer than 37 weeks
premature infants with respiratory distress syndrome
premature infants with respiratory distress syndrome who can extubate after surfactant therapy

Exclusion Criteria

congenital heart diseases
asphyxia
septic shock
multiple anomaly

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The extubation failure rate in two groups of NCPAP and HHFNC within 7 days after the intervention. Timepoint: within 7 days after INSURE(intubation and surfactant injection and extubation). Method of measurement: EXAMINATION AND STUDY OF FILES.;The length of oxygen requirement after surfactant therapy. Timepoint: during after surfactant therapy. Method of measurement: EXAMINATION AND STUDY OF FILES.

Secondary Outcome Measures

Name	Time	Method
Pneumotorax and air leaks of the plural space due to the two type of noninvasive ventilation during the period of receiving respiratory support. Timepoint: During the period of receiving noninvasive respiratory support (intervention). Method of measurement: EXAMINATION AND CXR AND STUDY OF FILES.;Intraventricular brain hemorrhage during the period of receiving respiratory support. Timepoint: During the period of receiving noninvasive respiratory support (the intervention). Method of measurement: examination and brain sonography.;Hospital length of stay. Timepoint: The total length of hospitalization of the studied neonates. Method of measurement: study of files.;Nasal trauma includes ulceration and necrosis during the period of receiving respiratory support. Timepoint: During the period of receiving respiratory support(the intervention). Method of measurement: inspection.