Effectiveness of Intravenous and intracoronary Vitamin C for the Prevention of Periprocedural Myocardial Injury And Contrast-Induced Acute Kidney Injury in Patients Undergoing Primary Percutaneous Coronary Intervention.

Vice Chancellor for research,Tehran University of Medical Sciences0 个研究点目标入组 110 人开始时间: 待定最近更新: 2018年2月22日

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•Subjects (men or women) at least 18 years and less than 80 years of age; Ischemic discomfort = 20 min and < 6 hours of duration; ST elevation = 1 mm (= 0.1mV) in two contiguous limb leads OR = 2mm (=0.2mV) in two contiguous precordial leads ; Planned primary PCI within 2 hours of hospital presentation; Planned or concomitant use of aspirin,
•clopidogrel, unfractionated heparin, and Glycoprotein IIb/IIIa inhibition with intent to stent the infarct-related artery; Informed consent able to be obtaine

•Age =80 years;
•Cardiac arrest or arrhythmia requiring chest compressions or cardiopulmonary resuscitation; Current warfarin therapy; Known allergy or contraindication to fibrinolvtics OR aspirin OR heparin OR clopidogrel; Patients with evidence of coronary collaterals (2-3 Rentrop) to the region at risk on previous coronary angiography (at the previous admission);Renal failure(creatinine>4.0 mg/dl).

发起方

Vice Chancellor for research,Tehran University of Medical Sciences