A Prospective Randomized Double-Blind Study on Prevention of Urethral Restenosis by Radiotherapy
Completed
- Conditions
- rethral stenosisUrological and Genital DiseasesUrethral stenosis
- Registration Number
- ISRCTN19584965
- Lead Sponsor
- niversity of Düsseldorf (Germany)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Male
- Target Recruitment
- 180
Inclusion Criteria
1. Peak flowrate <15 ml/s
2. Age >30
3. Stenosis suitable for internal urethrotomy
4. Written consent
Exclusion Criteria
1. Prior radiotherapy in this area (penis, prostate, bladder)
2. Cancer of the prostate or urethra or bladder
3. Congenital stenosis
4. Greater than three prior urethrotomies
5. Traumatic genesis
6. Stenosis >2 cm
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways does radiotherapy target to prevent urethral restenosis in ISRCTN19584965?
How does radiotherapy compare to endoscopic dilation in reducing urethral stenosis recurrence rates?
Which biomarkers correlate with successful urethral stenosis prevention via radiotherapy in clinical trials?
What are the long-term adverse events of low-dose radiotherapy for urethral restenosis prevention?
Are there combination therapies with radiotherapy for urological stenosis treatment in the University of Düsseldorf studies?