Role of Magnesium Sulphate drug in reducing muscle contraction during general anesthesia induction after giving succinylcholine and in reducing post op pain.

Not Applicable

Conditions: Health Condition 1: O- Medical and Surgical

Registration Number: CTRI/2019/09/021014

Lead Sponsor: Department of Anesthesiology and Critical Care

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

Patient with ASA grade 1 and 2 and of age group 18 to 60 years of either sex undergoing elective surgeries under general anaesthesia and willing to give a written and informed consent.

Exclusion Criteria

1. Patients not willing to be a part of this study.

2. Patients who are having known allergy to the study drugs.

3. SBP <100 mmHg and HR <60/min(hemodynamic instability).

4. Patients with history of myasthenia gravis, muscular dystrophy or any other neuromuscular disease.

5. Patients with history of epilepsy/seizure disorder.

6. Patients who are taking antihypertensive medications (hypertensive patient).

7. Pregnant patients.

8. Raised intracranial pressure, raised intraocular pressure, hypotension history, diabetics, neurological patients, burn patient, hyperkalemia patient, history of gastric reflux.

9. Patients taking analgesics.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fasciculations will be seen just after succinylcholine injection and graded as:- <br/ ><br> <br/ ><br>1. Nil (absent) <br/ ><br>2. Mild (fine fasciculations of eyes, face , neck or fingers without movement of limbs) <br/ ><br>3. Moderate (obvious muscle twitching at more than one sites or movement of limbs) <br/ ><br>4. Severe (vigourous, sustained and widespread fasciculations) <br/ ><br>Timepoint: Fasciculations will be seen just after giving succinylcholine injection

Secondary Outcome Measures

Name	Time	Method
Postoperative myalgia seen after 24 hours of surgery and graded as:- <br/ ><br> <br/ ><br>Grading <br/ ><br>1. Nil (absence of pain) <br/ ><br>2. Mild (muscle stiffness or pain on specific questioning in nape of neck, shoulders and lower chest on deep breathing) <br/ ><br>3. Moderate (muscle stiffness and pain complained of by the patient spontaneously requesting analgesia) <br/ ><br>4. Severe ( generalized muscle stiffness or pain which limits physical activity) <br/ ><br>5. Worst possible pain <br/ ><br>Timepoint: after 24 hours of surgery