Effect of magnesium sulphate on intraocular pressure
Not Applicable
Recruiting
- Conditions
- Intraocular pressure rise after suxamethonium administration in rapid sequence induction
- Registration Number
- PACTR201701001958143
- Lead Sponsor
- Fayoum University hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
age 18 - 95 years.
ASA 1 and 2.
Non-ophthalmic surgery.
Rapid sequence induction anaesthesia.
Exclusion Criteria
Patients with known hypersensitivity to magnesium sulphate or suxamethonium. Hypocalcemia.
Any degree of heart block.
Uncontrolled hypertension.
Patients with unstable hemodynamics or in need to inotropes or vasopressor support. Morbidly obese (BMI ¿ 40).
Any cardiovascular, renal, hepatic or muscular disease.
Patients with raised IOP.
Patients receiving any drug known to alter IOP.
Previous eye surgery.
Expected difficult intubation.
Require two or more attempts at laryngoscopy for endotracheal tube placement.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intraocular pressure (IOP)
- Secondary Outcome Measures
Name Time Method Mean arterial blood pressure (MAP);Heart rate (HR);Laryngoscopy time ;serum magnesium level;body mass index (BMI);Weight