Prediction of REsPonse to Antipsychotics using electRoEncephalography
Recruiting
- Conditions
- Psychotic illnessSchizophrenia10039628
- Registration Number
- NL-OMON52737
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
- Age between 16 and 55 years old
- Psychotic episode
- Patients who are going to start or recently have started antipsychotic
treatment (<2
weeks prior to baseline visit)
- The participant needs to understand the study and is able to provide written
informed consent.
Exclusion Criteria
- Coercive measures. With exception of zorg machtiging if a patient wants to
start with antipsychotics voluntarily and the patient is competent of making
decisions.
- A history of mental retardation
- Organic brain damage
- Organic psychosis
- Patients who are pregnant or patients who are breastfeeding.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>For the primary outcome, patients will be divided into a responder and a<br /><br>non-responder group based on the Positive and Negative Symptoms Scale (PANSS)<br /><br>scores and remission criteria as defined by Andreasen and others.<br /><br><br /><br><br /><br><br /><br><br /><br>*</p><br>
- Secondary Outcome Measures
Name Time Method <p> Secondary outcomes include improvement on questionnaires for the quality of<br /><br>life, general and physical health and functional outcome. Tertiary outcome<br /><br>includes continuous changes in psychosis symptom levels as measured by the<br /><br>PANSS.<br /><br><br /><br></p><br>