Assessment of Sleep Disturbance in Alzheimer Disease

Not Applicable

Completed

• Conditions: Alzheimer Disease
• Interventions: Other: Analysis of sleep disturbance

• Registration Number: NCT00831298
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

The purpose of this study is to study circadian rhythms, or daily cycles of sleep, wake, and activity. The investigators hope to learn how disturbed sleep in Alzheimer's Disease relates to changes in activity cycles, and how sleep disturbances may affect your daytime alertness.

This project selects patients suffering from memory problems, or voluntary to be in our Control Group. There are three parts to this study: Sleep Diaries, Behavioral Questionnaire, and Activity Recordings

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2009-01-27
• Study First Submitted QC: 2009-01-27
• Study First Posted: 2009-01-28
• Study Start: 2010-07
• Primary Completion: 2011-11
• Study Completion: 2011-11
• Status Verified: 2011-12
• Last Update Submitted: 2011-12-08
• Last Update Posted: 2011-12-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• alzheimer disease
• MMSE > 20
• over 65 years old

Exclusion Criteria

• new psychotropic drug treatment
• patient unable to do neuropsychologic tests

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Analysis of sleep disturbance	Behavioral Questionnaire Sleep Recordings Genetic analysis

Primary Outcome Measures

Name	Time	Method
assessment of apathy	at day 0, just after inclusion

Secondary Outcome Measures

Name	Time	Method
assessment of sleep disturbance	during a week, between day 0 and day 7
determine a genetic relationship between sleep disturbance and alzheimer disease	after all genetic analyses of the study

Trial Locations

Locations (1)

Centre Mémoire de Ressources et de Recherche, CHU de Nice; 🇫🇷 Nice, France