EEG signals predicting freezing of gait in Parkinson patients

Completed

Conditions: Freezing of gait in Parkinson's Disease
10028037

Registration Number: NL-OMON47712

Lead Sponsor: Radboud Universiteit Nijmegen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 15

Inclusion Criteria

* Men/women of age > 18 years with idiopathic Parkinson*s disease, as diagnosed by the UK Brain Bank Criteria.
* Written informed consent.
* Presence of FOG (defined as a score of 1 on question 1 Have you experienced FOG in the past month from the NFOGQ).
* Disabling/regular FOG (defined as a score of 3 Very often, more than one time a day on question 2 How often do you experience FOG from the NFOGQ).

Exclusion Criteria

* Comorbidities that cause severe gait impairment (e.g. severe arthrosis or neuropathy).
* Severe cognitive impairments (MMSE<24).
* Inability to walk 150 meters unaided.
* Bald (entirely) participants

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The following study parameters will be collected during the 1st and 2nd<br /><br>experiments. Both experiments will be video-taped and rated for the presence of<br /><br>FOG. The videos only can be accessed by researchers.<br /><br>o 64- and 32-channel EEG data will be acquired by ActiCap and TMSi EEG system<br /><br>from participants in both two experiments, respectively;<br /><br>o Gait parameters such as cadence will be calculated from 4 accelerometers on<br /><br>lower body of participants (TMSi, 4 sensors = 2 above ankles, 2 above knees);<br /><br>o Gait parameters related to the gait of upper body will be calculated<br /><br>from 2 accelerometers and 2 EMG sensors (TMSi) above metacarpophalangeal joints<br /><br>and forearms of participants, respectively ;<br /><br>o ECG data measured (TMSi);<br /><br>o Vertical forces of foot acquired by TMSi Footswitches.</p><br>

Secondary Outcome Measures