Efficacy of lignocaine with dexmedetomidine in comparison to lignocaine with adrenaline in mandibular third molar surgery: A randomised clincial trial

Phase 2

Completed

• Conditions: Health Condition 1: K011- Impacted teeth

• Registration Number: CTRI/2023/05/052189
• Lead Sponsor: Chhattisgarh Dental College and Research Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2024-01-14
• Last Update Posted: 1 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

1. ASA I (Healthy patients)

2. Patients with Pederson’s difficulty index score 5-6 (moderately difficult)

3. Patients willing for third molar extraction and participating in the study

Exclusion Criteria

1. Impacted third molars associated with acute infections or pathologies.

2. Pregnant and lactating females and patients on oral contraceptives.

3. Medically compromised patients (hypertension, bradycardia, hypotension, sinus disorder, liver disorders, renal impairment and uncontrolled diabetes)

4. Tobacco chewers and smokers.

5. Patients allergic to lignocaine with dexmedetomidine, lignocaine, and adrenaline

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To study the efficacy of dexmedetomidine combined with 2% lignocaine on: <br/ ><br>Onset of Anesthesia <br/ ><br>Duration of Anesthesia <br/ ><br>Pain <br/ ><br>Edema <br/ ><br>Mouth OpeningTimepoint: 24 hours, 72 hours, 120 hours, 168 hours

Secondary Outcome Measures

Name	Time	Method
To compare the efficacy of 2% lignocaine combined with dexmedetomidine to 2% lignocaine with 1:80,000 adrenalineTimepoint: 24 hours, 72 hours, 120 hours, 168 hours