the Ethics Committee of the First Affiliated Hospital of Nanchang University
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,879
- 主要终点
- overall survival
研究概览
简要总结
The goal of this observational study is to evaluate the short-term outcomes and long-term outcomes of robot-assisted right colon group for cancer compared to laparoscopic-assisted right colon group. This is a large sample study based on ten years of clinical data. The main question it aims to answer is: What are the advantages of da Vinci robot right hemicolectomy compared to laparoscopic right hemicolectomy, and is there a difference in long-term efficacy between the two methods.
详细描述
Colorectal cancer (CRC) is highly prevalent worldwide. In China, CRC ranks high among the population of men and women with cancer. The incidence and mortality rates of CRC are rising quickly in developing countries, and it is the fourth most deadly cancer in the world. In particular, the right colon cancer (RCC) is continuously growing in China, and the early symptoms of RCC are not typical. one of the most useful ways for RCC is surgical is a surgical operation. Along with the development of minimally invasive surgery, the use of laparoscopy for colon cancer is widely accepted and has become one symbolic surgical technology. Studies have demonstrated that laparoscopic colonic surgery is related to reduced pain after operation, shorter rehabilitation time, shorter length of hospital stay, reduced the time of ileus after surgery, and reduced surgical site infection.
Nevertheless, laparoscopic surgery also has its shortcoming, including a limited range of motion, slow learning and growth, and physiological tremor cannot be eliminated.The emergence of robots has broken the inherent disadvantage of laparoscopy. It has achieved similar or better results in previous studies. Based on these advantages, robotic surgery has received much attention from the surgeons. With the first robotic surgery in the field of colon cancer was reported in 2002, there are some studies proved the safety and feasibility by using robot,However, most studies with small sample sizes and with cases at a relatively early stage.
Therefore, the purpose of this study is to compare the short-term and long-term outcomes between RARC and LARC in the treatment of right colon cancer in our center.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The age is more than 18 years old and less than or equal to 85 years old
- •No distant metastasis (including pelvic cavity, peritoneum, liver, lung, brain, bone, distant lymph node metastasis, etc.) is judged by ultrasound, CT, PET-CT, etc
- •Preoperative colonoscopy showing that the tumor was located in the ileocecal region, ascending colon, hepatic flexure, or transverse colon with pathology showing malignancy
- •signed informed consent. -
排除标准
- •multiple primary colorectal cancer
- •recurrent right colon cancer
- •preoperative neoadjuvant chemotherapy
- •emergency surgery for intestinal obstruction, bleeding or perforation
- •incomplete data and missing follow-up data. -
结局指标
主要结局
overall survival
时间窗: 5 years after surgery
months
disease-free survival
时间窗: 5 years after surgery
months
次要结局
- estimation of blood loss(Intraoperative)
- days after postoperative hospital stay(1 months after surgery)
- the rate of postoperative complications(1 months after surgery)
- number of retrieved lymph nodes(Intraoperative)
- operative time(Intraoperative)
- time to liquid diet(1 weeks after surgery)
- the rate of intracorporeal anastomosis(1 months after surgery)
- time to first exhaust(1 weeks after surgery)
研究者
Taiyuan Li
the First Affiliated Hospital of Nanchang University
Nanchang University