Effect of Intraarticular Injection of Tenoxicam and Hyaluronic Acid Versus Platelet-Rich Plasma and Hyaluronic Acid in Temporomandibular Joint Internal Derangement

Phase 1

Active, not recruiting

• Conditions: Temporomandibular Joint Internal Derangement

• Registration Number: NCT06572904
• Lead Sponsor: Mansoura University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-8-23
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Inclusion Criteria:<br><br> 1. Patients age must be (18 -45).<br><br> 2. Patients have painful joint, clicking sound, with or without limited mouth opening.<br><br> 3. patients are unresponsive to conservative treatment.<br><br> 4. Patient's ability and desire to complete the treatment protocol and follow-up<br> visits.<br><br> 5. Patients with internal derangement with reduction confirmed by MRI imaging.<br><br>Exclusion Criteria:<br><br> 1. Patient with an inflammatory or connective tissue disease<br><br> 2. Patient with previous invasive TMJ surgical procedure.<br><br> 3. Neurologic disorders<br><br> 4. History of injection of any substance into the target TMJ during previous 6 months.<br><br> 5. History of drug allergy.<br><br> 6. Patient with a history of bony or fibrous adhesion.<br><br> 7. Malignant disease in the head and neck region.<br><br> 8. TMJ Internal derangement without reduction.<br><br> 9. Patients respond to conservative treatment. 10.Patient with a psychological problem<br><br>11.Patients having gross mechanical restrictions and condylar fracture

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intracapsular Pain and pain during movement;Clicking sound;Maximum inter-incisal opening (MIO)

Secondary Outcome Measures

Name	Time	Method
Magnetic Resonance Imaging (MRI) evaluation