Effects of krill oil on knee joint pai

Not Applicable

• Conditions: Knee joint pain

• Registration Number: JPRN-UMIN000014413
• Lead Sponsor: Juntendo University, Graduate School of Health & Sports Science

Brief Summary

Both the placebo and krill oil groups showed significant improvements in the questions in the JKOM and JOA questionnaires after administration. After the intervention, krill oil group showed more improvements than placebo group in two questions regarding the pain and stiffness in knees in JKOM. Controlling for age, sex, weight, and smoking and drinking habits, krill oil significantly mitigated knee pain in sleeping (P < 0.001), standing (P < 0.001) and the range of motion of both right and left knees (both P = 0.011) compared to placebo. Krill oil administration raised plasma EPA (P = 0.048) and EPA/AA ratio (P = 0.003).

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-07-15
• Study Completion: 2015-04-20
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

1) a patient treated with biological agent(s) 2) a patient judged inadequate to enter the trial by orthopedist

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Japanese Knee Osteoarthritis Measure (JCOM), The Japanese Orthopedic Association knee rating score (JOA score)

Secondary Outcome Measures

Name	Time	Method
C-reactive protein, MMP-3, hyaluronic acid (HA), Range of motion (ROM) of the knee, etc.