CTRI/2025/12/099861尚未招募不适用
ASSOCIATION OF GHRELIN GENE (GHRL) POLYMORPHISM (rs4684677) WITH COGNITIVE STATUS IN T2DM
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 90
- 试验地点
- 1
研究概览
简要总结
The primary aim is to detect GHRL rs4684677 polymorphism and measure plasma ghrelin levels alongside cognitive function in T2DM patients versus controls. T2DM drives cognitive decline via insulin resistance and inflammation, with ghrelin offering neuroprotective potential. This study links genetic variation, hormone levels, and MoCA-assessed cognition to elucidate early DCI mechanisms
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 35.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •For Cases:Known diabetic patients diagnosed with T2DM,atleast for the last 5 years as per ADA criteria.On treatment,without any other known metabolic,surgical,or psychiatric comorbid condition.
- •For Control:Healthy volunteers.
排除标准
- •For Cases: Patient admitted with acute complications of Diabetes mellitus.
- •For Control: history of any substance abuse which may affect cognitive function.
研究者
Dr Smita Kaushik
Maulana Azad Medical College
研究点 (1)
Loading locations...
相似试验
尚未招募
不适用
Checking whether certain genetic variations are linked to gum disease in people from South IndiaCTRI/2026/03/105541Helen Reshma K176
Unknown
不适用
Gitelman 综合征基因型和表型特征的临床研究Gitelman 综合征ChiCTR2100048977自筹经费30
Unknown
不适用
人类 EGFR/ALK/ROS1/RET/KRAS/NRAS/ PIK3CA/BRAF/ HER2/MET 基因突变检测试剂盒（可逆末端终止测序法）的研究非小细胞肺癌ChiCTR2100053481申办方：福建和瑞基因科技有限公司
Unknown
1 期
TIM-3 及 Th17 细胞在吉兰-巴雷综合征中的作用ChiCTR-CNRC-10000861自筹120
招募中
Unknown
MRKH 综合征发病相关基因筛查及干预研究MRKH 综合征ChiCTR1900025238温州市重点妇科肿瘤研究所(No. ZD201603).60