Comparison of Oral Isotretinoin vs Ancomparison of Oral Isotretinoin vs Antibiotics on Corneal Thickness With AV
Not Applicable
Active, not recruiting
- Conditions
- Cornea
- Interventions
- Diagnostic Test: Oral IsotretinoinCombination Product: Antibiotics
- Registration Number
- NCT06483971
- Lead Sponsor
- Superior University
- Brief Summary
Comparison of Oral Isotretinoin versus comparison of Oral Isotretinoin versus Antibiotics on Corneal Thickness in Patients with Acne Vulgaris
- Detailed Description
Acne is the most common skin disease requiring attention of health practitioners. It is a self-limiting disease of the pilosebaceous unit, which can lead to devastating and frustrating scars and pigmentary alterations.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 36
Inclusion Criteria
- Patients of either gender shall be enrolled for this study.
- Acne vulgaris patients taking oral isotretinoin and oral antibiotics shall be included.
Exclusion Criteria
- Patients with any ocular pathology shall be excluded.
- Patients with any systemic pathology other than acne vulgaris shall be excluded.
- Patients with history of contact lens wear, previous refractive surgery or injury shall be excluded.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Oral Isotretinoin Oral Isotretinoin - Antibiotics Antibiotics -
- Primary Outcome Measures
Name Time Method Optical Coherence Tomography (OCT) 12 Months Standardized OCT imaging protocols to ensure consistency and accuracy across all measurements.
Snellen Chart 12 months Visual acuity measured at 3-month and 6-month intervals. Units: Snellen fraction (e.g., 20/20, 20/40)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Shalamar Hospital Mughalpura
🇵🇰Lahore, Punjab, Pakistan