Enhancing placebo effects in pain and itch through oxytoci
Completed
- Conditions
- Het onderzoek wordt bij gezonde personen uitgevoerd. Het onderzoek kan voor nieuwe inzichten zorgen bij therapeutische interventies voor pijn en jeuk.not applicable
- Registration Number
- NL-OMON42756
- Lead Sponsor
- niversiteit Leiden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
- Female between 18 and 35 years old
- Good understanding of written and spoken Dutch
Exclusion Criteria
- Refusal to give written informed consent
- Pregnancy or breast feeding
- Conditions that might interfere with the participant's safety and/or the study protocol: severe somatic or psychological morbidity (e.g., heart and lung diseases, or DSM-IV psychiatric disorders, Raynaud*s phenomenon)
- Chronic or acute itch or pain complaints
- Current use of analgesics, anti-inflammatory drugs, antihistamines, antibiotics
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameters are self-reported pain in response to the Cold<br /><br>Pressor Test and self-reported itch in response to the histamine iontophoresis.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary parameters are skin temperature, flare response, and wheal size in<br /><br>response to the histamine iontophoresis, unpleasantness ratings in response to<br /><br>the Cold Pressor Task. Furthermore, the possible influence of psychological<br /><br>parameters on outcomes will be explored as well. </p><br>