microcirculatory perfusion in living kidney donors

Completed

• Conditions: cardiovascular disease; 10019280

• Registration Number: NL-OMON46695
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Age > 18
Living kidney donors
Provision of written informed consent

Exclusion Criteria

If candidate cannot understand Dutch or English.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main endpoint is to assess if perfused vessel density (PVD) in living<br /><br>kidney donors will be decreased after donation</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1) total vessel density (TVD)<br /><br>2) eGFR<br /><br>3) serum RAAS markers (aldosterone/renine ratio), FGF-23, insulin resistance<br /><br>markers (HOMA-IR), inflammation markers (hs-CRP and IL-6) levels </p><br>