Comparison of platelet rich plasma and triamcinolone in patient of osteoarthritis of knee for pain relief.

Not yet recruiting

• Conditions: Osteoarthritis of knee, unspecified, (2) ICD-10 Condition: M179||Osteoarthritis of knee, unspecified, (3) ICD-10 Condition: M171||Unilateral primary osteoarthritisof knee, (4) ICD-10 Condition: M171||Unilateral primary osteoarthritisof knee,

• Registration Number: CTRI/2022/04/042058
• Lead Sponsor: Government medical college bhavnagr

Brief Summary

After taking approval from ethic committee,study will be initiated on patient fulfilling inclusion criteria ,pt will be assessed for pain decrement by VAS Score ,function and  mobility increment and generic healthimprovement  by  KOOS score (Kneeinjury and OA Outcome) (at 6 week)&prevention and  slowing of the progress of disease  by KELLGREN & LAWRENCE Grade  (at 3 months ) between two group.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-04-21
• Study Start: 2022-04-28

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1)Grades I , II, III Knee OA according to criteria of American college of rheumatology 2)History of chronic pain > 3 month duration 3)Swelling of knee > 4 month 4)X-ray diagnosis ( Kellgren Lawrence 1 and 2).

Exclusion Criteria

1)Knee joint deformities 2)Acute infection 3)H/o knee surgery 4)H/o diabetes mellitus 5)H/o rheumatoid arthritis, gout H/o severe cardio vascular disorder, 5)haematological disorders, renal disorder Immunodeficiency 6)Patients taking anticoagulants 7)Patients with haemoglobin values of <10 and platelets values of <1,50,000/mm3 8)H/o vasovagal shock 9)Pregnant and lactating females 10)H/o corticosteroid consumption within last 3 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1)To compare pain decrement by VAS Score ( Visual analogue score).	1)To compare pain decrement by VAS Score ( Visual analogue score). | T2)o compare function and mobility increment and generic health improvement by KOOS score (Knee injury and OA Outcome)(at 6 week) | 3)To compare prevention and slowing of the progress of disease by KELLGREN & LAWRENCE Grade (at 3 months ) between two group.
T2)o compare function and mobility increment and generic health improvement by KOOS score (Knee injury and OA Outcome)(at 6 week)	1)To compare pain decrement by VAS Score ( Visual analogue score). | T2)o compare function and mobility increment and generic health improvement by KOOS score (Knee injury and OA Outcome)(at 6 week) | 3)To compare prevention and slowing of the progress of disease by KELLGREN & LAWRENCE Grade (at 3 months ) between two group.
3)To compare prevention and slowing of the progress of disease by KELLGREN & LAWRENCE Grade (at 3 months ) between two group.	1)To compare pain decrement by VAS Score ( Visual analogue score). | T2)o compare function and mobility increment and generic health improvement by KOOS score (Knee injury and OA Outcome)(at 6 week) | 3)To compare prevention and slowing of the progress of disease by KELLGREN & LAWRENCE Grade (at 3 months ) between two group.

Secondary Outcome Measures

Name	Time	Method
1)To compare analgesic requirement during the study period between two group.	2)To compare need of surgical intervention require during study period Between two group.

Trial Locations

Locations (1)

Government medical college bhavnagar; 🇮🇳 Bhavnagar, GUJARAT, India

Government medical college bhavnagar

🇮🇳Bhavnagar, GUJARAT, India

Jankiben Panchal

Principal investigator

6354517097

panchaljanki222@gmail.com