Comparision of the analgesic effect of intraarticular platelet rich plasma and triamcinolone in patient of osteoarthritis knee - randomized control trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- 1)To compare pain decrement by VAS Score ( Visual analogue score).
研究概览
简要总结
After taking approval from ethic committee,study will be initiated on patient fulfilling inclusion criteria ,pt will be assessed for pain decrement by VAS Score ,function and mobility increment and generic healthimprovement by KOOS score (Kneeinjury and OA Outcome) (at 6 week)&prevention and slowing of the progress of disease by KELLGREN & LAWRENCE Grade (at 3 months ) between two group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 35.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Grades I , II, III Knee OA according to criteria of American college of rheumatology 2)History of chronic pain > 3 month duration 3)Swelling of knee > 4 month 4)X-ray diagnosis ( Kellgren Lawrence 1 and 2).
排除标准
- •Knee joint deformities 2)Acute infection 3)H/o knee surgery 4)H/o diabetes mellitus 5)H/o rheumatoid arthritis, gout H/o severe cardio vascular disorder, 5)haematological disorders, renal disorder Immunodeficiency 6)Patients taking anticoagulants 7)Patients with haemoglobin values of <10 and platelets values of <1,50,000/mm3 8)H/o vasovagal shock 9)Pregnant and lactating females 10)H/o corticosteroid consumption within last 3 months.
结局指标
主要结局
1)To compare pain decrement by VAS Score ( Visual analogue score).
时间窗: 1)To compare pain decrement by VAS Score ( Visual analogue score). | T2)o compare function and mobility increment and generic health improvement by KOOS score (Knee injury and OA Outcome)(at 6 week) | 3)To compare prevention and slowing of the progress of disease by KELLGREN & LAWRENCE Grade (at 3 months ) between two group.
T2)o compare function and mobility increment and generic health improvement by KOOS score (Knee injury and OA Outcome)(at 6 week)
时间窗: 1)To compare pain decrement by VAS Score ( Visual analogue score). | T2)o compare function and mobility increment and generic health improvement by KOOS score (Knee injury and OA Outcome)(at 6 week) | 3)To compare prevention and slowing of the progress of disease by KELLGREN & LAWRENCE Grade (at 3 months ) between two group.
3)To compare prevention and slowing of the progress of disease by KELLGREN & LAWRENCE Grade (at 3 months ) between two group.
时间窗: 1)To compare pain decrement by VAS Score ( Visual analogue score). | T2)o compare function and mobility increment and generic health improvement by KOOS score (Knee injury and OA Outcome)(at 6 week) | 3)To compare prevention and slowing of the progress of disease by KELLGREN & LAWRENCE Grade (at 3 months ) between two group.
次要结局
- 1)To compare analgesic requirement during the study period between two group.(2)To compare need of surgical intervention require during study period Between two group.)