The Protein StudyThe effect of protein intake on circulating inflammatory markers in women with obesity

Not Applicable

Recruiting

• Conditions: Inflammatory markers and insulin secretion in obese women after ingestion of protein, protein and carbohydrate meals, or carbohydrate only meals; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12608000450314
• Lead Sponsor: niversity of Otago

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-09-15
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 25

Inclusion Criteria

25 abdominally obese women Body Mass Index (BMI) > 30 and waist circumference > 88cm)

Exclusion Criteria

Cigarette smoking, cardiovascular disease, infections or other serious medical problems and use of some medications

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Whether ingestion of protein and especially dairy protein, increases the secretion of insulin and thus it's anti-inflammatory activity. The plasma insulin secretion will be measured using a commercial kit (Roche) on a Hitachi E170 autoanalyser.[The insulin levels will be measured at baseline, 1 hour and 4 hour intervals after consuming the meals.];Markers of inflammation-Plasma levels of IL-6, will be measured by Enzyme-Linked ImmunoSorbent Assay (ELISA) using a commercial kit (R&D Systems) Plasma Free fatty acid levels will be measured using a commercial kit from Roche Diagnostics.[All these blood samples will be taken at baseline, 1 hour and 4 hours after the meal.]

Secondary Outcome Measures

Name	Time	Method
Plasma Glucose will be measured by a routine method in the hospital diagnostic laboratory.[All these blood samples will be taken at baseline, 1 hour and 4 hours after the meal.]