Pilot Study: Effects of transcranial Direct Current Stimulation (tDCS) on cognitive functioning in regular, long-term cannabis consumers

niversity of Tasmania0 sites20 target enrollmentMarch 20, 2019

Overview

No summary available.

Registry

who.int

Start Date

March 20, 2019

End Date

March 19, 2020

Last Updated

6 years ago

Study Type

Interventional

Sex

All

Sponsor

niversity of Tasmania

•General inclusion criteria: 18\-50 years old, male and female, English\-speakers, normal or corrected\-to\-normal vision
•Cannabis group inclusion criteria: Individuals who have regularly (1\+ days per week) used cannabis for 1\+ year. We are not specifically recruiting individuals with cannabis use disorder (CUD); however, participants may meet criteria for CUD. Cannabis users will be asked to refrain from cannabis use 24 hours \+ prior to the Research Session.
•Control group: No history of cannabis use or minimal (\<50 lifetime uses) history of cannabis use

•General exclusion criteria:
•No current or recent illicit drug use (in the past 30 days)
•Dependence on alcohol (a dependency score of 20 or more on the Alcohol Use Disorder Identification Test) or other illicit substances, except nicotine
•Pregnancy or suspected pregnancy
•Known psychological problems (e.g., depression, anxiety, schizophrenia, PTSD); participants who self\-report a clinical diagnosis will be excluded from the study,
•Physical conditions or problems (such as cardiac problems and using related medication such as beta\-blockers)
•Metabolic diseases that would confound measures of metabolites (e.g., renal and kidney disease, phenylketonuria/PKU, tyrosinemia)
•Use of prescribed medications to treat psychological conditions (e.g., anxiolytics, antidepressants) due to the potential interactive effect between tDCS and particular medications that could affect measures of cortical excitability
•Brain stimulation contraindications:
•Epilepsy or family history of epilepsy