ACTRN12619000462189终止未知
Pilot Study: Effects of transcranial Direct Current Stimulation (tDCS) on cognitive functioning in regular, long-term cannabis consumers
niversity of Tasmania0 个研究点目标入组 20 人开始时间: 2019年3月20日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 终止
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 50 Years（—）
- 性别
- All
入选标准
- •General inclusion criteria: 18-50 years old, male and female, English-speakers, normal or corrected-to-normal vision
- •Cannabis group inclusion criteria: Individuals who have regularly (1+ days per week) used cannabis for 1+ year. We are not specifically recruiting individuals with cannabis use disorder (CUD); however, participants may meet criteria for CUD. Cannabis users will be asked to refrain from cannabis use 24 hours + prior to the Research Session.
- •Control group: No history of cannabis use or minimal (<50 lifetime uses) history of cannabis use
排除标准
- •General exclusion criteria:
- •No current or recent illicit drug use (in the past 30 days)
- •Dependence on alcohol (a dependency score of 20 or more on the Alcohol Use Disorder Identification Test) or other illicit substances, except nicotine
- •Pregnancy or suspected pregnancy
- •Known psychological problems (e.g., depression, anxiety, schizophrenia, PTSD); participants who self-report a clinical diagnosis will be excluded from the study,
- •Physical conditions or problems (such as cardiac problems and using related medication such as beta-blockers)
- •Metabolic diseases that would confound measures of metabolites (e.g., renal and kidney disease, phenylketonuria/PKU, tyrosinemia)
- •Use of prescribed medications to treat psychological conditions (e.g., anxiolytics, antidepressants) due to the potential interactive effect between tDCS and particular medications that could affect measures of cortical excitability
- •Brain stimulation contraindications:
- •Epilepsy or family history of epilepsy
- •History of neuropsychiatric conditions (e.g., stroke)
- •Skin compromised by pre-existing or current burns (e.g., sun burn), injuries, or conditions affecting the scalp (eczema or psoriasis on the head)
- •Pre-existing implants such as pacemakers and metal implants (excluding dental work such as tooth fillings, dental implants and non-ferromagnetic material). Any implant that is conductive, ferromagnetic or contains other magnetic-sensitive metals such as cochlea implants, stents, or implanted stimulators are contraindicated for TMS
- •Implanted electronic devices or intracranial magnetic clips such as aneurysm clips
- •Serious head injury or neurosurgery
研究者
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