evaluation of bone formation and blood supply around zirconium and titanium implants

Not yet recruiting

• Conditions: edentulous patients

• Registration Number: CTRI/2019/03/018286
• Lead Sponsor: korada sai sirisha

Brief Summary

Titaniumhas become a gold standard as a base for implant placement. Thenewly emerging Zirconia implants are bio compatible and mechanically stable. Conebeam Computed tomography (CBCT) can be used for the objective quantification ofdirect density measurements of bone, expressed in Hounsfield units (HU) andbonequality changes by fractal dimension analysis.

Doppler ultrasonographyis a non-invasive, accurate and simple technique to measure continuousmicrocirculatory blood flow in  peri- implant soft tissues .Theobjectives of this study:To compare andevaluate   bonemineral density in Hounsfield units (HU) in Zirconium and Titanium implants .  Tocompare and evaluate trabecular bone microstructure by Fractal Dimension(FD) in Zirconium and Titaniumimplants.  To compare evaluate crestal bone loss in Zirconium and Titanium dentalimplants. To compare peri-implant vascularity of Zirconium and Titanium dental implants. Patients attending outpatient department of  Periodontics St Joseph Dental College (SJDC). Patientsin mean age group between 25 to 55 years and partially edentulous areas will berandomly selected for double blind clinical trial. 20 implants will be placed usingroll of dice method . All the patients will be assessed for Bone MineralDensity (BMD) in Hounsfield units (HU) and Trabecular bonemicrostructure by Fractal Dimension (FD) analysis using CBCT and crestal bone loss using RVG aroundZirconium and Titanium implants at baseline and one year after placement ofimplants.

Vascularflow in peri-implant mucosa will also be assessed by ultrasound Dopplerflowmetry at baseline (before placement of the Implant) and on the 10th daypost operatively.

Inclusioncriteria:

•       Patients of mean agegroup between 25 to 55 years.

•       Patients with one or moreedentulous site in either maxilla or mandible.

•       Good systemic health.

          Exclusioncriteria:

•      Any systemic disease thataffects the periodontium are contraindicated for implant placement.

•      Patients with psychiatricdisorders.

•      Inability orunwillingness to complete the trial

•      Poor oral hygiene

•      Pregnant,lactating mothers.

•      Historyof smoking and alcohol

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-04
• Last Update Posted: 2019-03-25

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

adult males or females with one or more edentulous site in either maxilla or mandible and patients with good systemic health.

Exclusion Criteria

• any systemic illness that effects periodontium are contraindicated for implant placement.patients with psychiatric disorders.inability or unwillingness to complete the trial.poor oral hygiene.
• pregnant, lactating mothers.
• history of smoking and alcohol.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
immeditely after implant placement	base line and after 10 days

Secondary Outcome Measures

Name	Time	Method
after osseointegration of implants	after 12 months

Trial Locations

Locations (1)

DUGGIRALA; 🇮🇳 Godavari, ANDHRA PRADESH, India

DUGGIRALA

🇮🇳Godavari, ANDHRA PRADESH, India

korada sai sirisha

Principal investigator

9553266377

saisirishakorada77@gmail.com