Genetic and Neural Factors in Alcohol-Related Cognition
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 9
- Locations
- 1
- Primary Endpoint
- Changes in Alcohol-influenced Behavior
Study Overview
Brief Summary
This study examines the genetic factors that impact cognitive processes and behavior after alcohol consumption. Participation in this project will contribute to a better understanding of cognitive factors that influence alcohol misuse.
Detailed Description
Some study details are purposely omitted at this time to preserve scientific integrity. Full details will be posted at the conclusion of the study.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Basic Science
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 21 Years to 45 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •English speaking
- •No current or regular use of prescribed or illicit psychoactive drugs
- •Free of major health problems (e.g., diabetes, HIV, Parkinson's disease)
- •Free of neurological or psychiatric disorders
- •No current drug abuse (e.g., recreational drug use).
- •Right-hand dominant
- •Free of claustrophobia
- •Free of pregnancy or suspected pregnancy
- •Absent MRI risk factors (e.g., implanted medical device, body mass index > 35, braces)
- •Free of medical conditions that render individuals with overly sensitive hearing
- •Non-naive to alcohol consumption
Exclusion Criteria
- •Not meeting the inclusion criteria listed above
Outcomes
Primary Outcomes
Changes in Alcohol-influenced Behavior
Time Frame: During the course of the MRI session
Aggressive behavior (i.e., the average volume of noise blasts selected to be administered to participants' opponents) after recent consumption of an alcoholic beverages (versus without recent consumption of an alcoholic beverages) will be measured using the validated and computerized Taylor Competitive Reaction-Time Task. The Taylor Competitive Reaction-Time Task consists of multiple trials that each assess aggression, via a four-point scale that ranges from 1 (low noise blast volume \[low aggression\]) to 4 (high noise blast volume \[high aggression\]). Noise blast settings are averaged to provide a total score ranging from 1 to 4, with higher scores indicating greater aggression.
Secondary Outcomes
No secondary outcomes reported