Genetic and Neural Factors in Alcohol-Related Cognition

Not Applicable

Completed

• Conditions: Alcohol Abuse
• Interventions: Behavioral: MRI Scanner

• Registration Number: NCT03725345
• Lead Sponsor: Virginia Commonwealth University

Brief Summary

This study is about how genetic and brain factors impact cognitive processes and behavior after alcohol consumption. Participation in this project will contribute to a better understanding of biological factors that influence alcohol misuse. This study will be completed in two laboratory visits.

Detailed Description

Some study details are purposely omitted at this time to preserve scientific integrity. Full details will be posted at the conclusion of the study.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2018-10-29
• Study First Submitted QC: 2018-10-29
• Study First Posted: 2018-10-31
• Study Start: 2023-07-11
• Primary Completion: 2024-04-25
• Study Completion: 2024-04-25
• Status Verified: 2024-10
• Last Update Submitted: 2024-10-02
• Last Update Posted: 2024-10-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 808

Inclusion Criteria

• English speaking
• No current or regular use of prescribed or illicit psychoactive drugs
• Free of major health problems (e.g., diabetes, HIV, Parkinson's disease)
• Free of a neurological or psychiatric disorders
• No current drug abuse (e.g., recreational drug use).
• Right hand dominant
• Free of claustrophobia
• Free of pregnancy or suspected pregnancy
• Absent MRI risk factors (e.g., implanted medical device, body mass index > 35, braces)
• Free of medical conditions that render individuals with overly sensitive hearing
• Non-naive to alcohol consumption

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Exclusion Criteria

• Not meeting inclusion criteria listed above

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
No Alcohol Group	MRI Scanner	Participants who have not recently consumed alcohol.
Alcohol Group	MRI Scanner	Participants who have recently consumed alcohol.

Primary Outcome Measures

Name	Time	Method
Changes in alcohol-influenced behavior	Approximately 7 days between alcohol consumption.	Competitive reaction-time behavior after recent consumption of an alcoholic beverages (versus without recent consumption of an alcoholic beverages) will be measured using the validated and computerized Taylor Competitive Reaction-Time Task. Some outcome measure details are purposely omitted at this time to preserve scientific integrity.

Trial Locations

Locations (1)

Virginia Commonwealth University; 🇺🇸 Richmond, Virginia, United States