To study the effects of sedative drug- dexmedetomidine- during general anaesthesia for endoscopic pituitary surgery.
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Scheduled for trans-sphenoidal pituitary surgery
- Registration Number
- CTRI/2018/03/012630
- Lead Sponsor
- PGIMER Chandigarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
40 ASA I-II patients between 18-65 years of age, scheduled for elective trans-sphenoidal pituitary surgery
Exclusion Criteria
Patients with following conditions:
1.Decreased level of consciousness
2.Increased intracranial pressure
3.Risk of impending cerebral herniation 4.Anticipated elective postop ventilation
5.Co-existing intracranial lesions like aneurysms or arteriovenous malformations
6.Significant cardiovascular co-morbidity like unstable angina, recent myocardial infarction, coronary artery bypass surgery, refractory arrhythmias, severe hypertension, congestive heart failure,
7.Those with severe respiratory disease such as bronchial asthma
8.Those with body weight more than 130% of ideal body weight
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Haemodynamic changes in mean arterial blood pressure and heart rateTimepoint: During procedure-every 10 minutes
- Secondary Outcome Measures
Name Time Method Bleeding in surgical fieldTimepoint: During procedure;Isoflurane requirementTimepoint: During procedure;Recovery parametersTimepoint: Immediate postop