New, Previously Unknown, Uses of Optical Coherence Tomography Angiography (OCTA)

Completed

• Conditions: Sickle Cell Retinopathy
• Interventions: Device: Optical Coherence Tomography Angiography

• Registration Number: NCT03068702
• Lead Sponsor: Dr. S.S. Michel Clinic

Brief Summary

Sickle cell maculopathy was sparingly mentioned in the literature before despite the fact that sickle cell disease or sickle cell trait is common in people of many areas of the world. This study shows that OCTA is a very valuable, non invasive, office procedure that may well be used in diagnosing this disease.

Detailed Description

this is a clinical study of two African Canadian patients that were diagnosed with sickle cell trait. I used OCTA to show macular vascular occlusions that usually happen with this disease.

Study Timeline

• Study Start: 2016-08-21
• Primary Completion: 2017-01-12
• Status Verified: 2017-02
• Study Completion: 2017-02-21
• Study First Submitted: 2017-02-22
• Study First Submitted QC: 2017-03-01
• Last Update Submitted: 2017-03-01
• Study First Posted: 2017-03-03
• Last Update Posted: 2017-03-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2

Inclusion Criteria

people with sickle cell trait or sickle cell disease -

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
African Canadians	Optical Coherence Tomography Angiography	African Canadians with sickle cell disease maculopathy diagnosed by OCTA.

Primary Outcome Measures

Name	Time	Method
vascular changes seen in the macular vasculature of people with sickle cell disease/ trait as compared to macular vasculature of normal macula.	through study completion, an average of one year	in this angiography the delicate vasculature of the macula can be clearly visualized and documented.