comparing the effectiveness of nebulization by 2 drugs in reducing sore throat after surgery

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2023/03/050439
• Lead Sponsor: DR KIRAN A V

Brief Summary

Patients who areundergoing elective surgeries done under general anaesthesia with endotracheal intubationand satisfies our study inclusion criteria in a year will be selected.Patients will be receivingeither nebulization Dexamethasone 8 mg [2ml] with 3 ml normal saline (or)   nebulization Lignocaine 2%  100mg [5 ml ] 30 min prior to induction of general anaesthesia.The occurrence of sore throat, post operative hoarseness, cough and if any side effects will be assessedpostoperatively for 24h.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-03-03
• Study Start: 2023-03-23

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

• 1.Patients belonging to American Society of Anaesthesiologists Physical Status grade I and II.
• 2.Patients posted for elective surgeries under general anaesthesia with tracheal intubation less than 4 hours.
• 3.Patients between age group 18 to 60 years.
• 4.Patients willing to give informed consent to participate in the study.
• 5.Mallampatti grade I and II.
• 6.Laryngoscopy done by experienced anaesthesiologist in single attempt.

Exclusion Criteria

• 1.Patients with known hypersensitivity or contra-indications to study drugs.
• 2.Received drugs(other than study drugs) that prevent sore throat, 24 hours before anaesthesia..
• 3.Patients with Body mass index more than 30.
• 4.ASA grade III and IV 5.Mallampatti III and IV 6.History of URTI in previous 2 weeks 7.H/O smoking 8.More than 2 attempts at laryngoscopy and intubation 9.Patients who are on steroids 10.Patients requiring manipulation of airway or instrumentation(like oral airway,stylet,bougie, external laryngeal maneuver) 11.Pregnant patients.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of dexamethasone nebulization versus lignocaine nebulization in prevention or reduction of post operative sore throat(POST)	0 hour , 2 hours , 4 hours , 6 hours , 12 hours , 24 hours

Secondary Outcome Measures

Name	Time	Method
To compare the efficacy of dexamethasone nebulization versus lignocaine nebulization in prevention or reduction of post operative hoarseness and cough.	0 hours , 2 hours , 4 hours , 6 hours , 12 hours , 24 hours

Trial Locations

Locations (1)

MIMS, Mandya; 🇮🇳 Mandya, KARNATAKA, India

MIMS, Mandya

🇮🇳Mandya, KARNATAKA, India

DR KIRAN A V

Principal investigator

8867917802

virupaksha2614@yahoo.com