A clinical trial to study the effects of dexamethasone nebulization and magnesium sulphate nebulization in patients with post operative sore throat.

Phase 3

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2019/12/022499
• Lead Sponsor: INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCES PATNA

Brief Summary

Post operative sore throat is one of the common complication  of laryngoscopy and endotracheal intubation. Different agents like lignocaine jelly, ketamine gargles, iv dexamethasone, magnesium sulphate gargles & lozenges have been used with variable  success in decreasing the incidence and severity of post operative sore throat. This is  a comparativetudy to see the effects of nebulization dexamethasone and magnesium sulphate in incidence and severity of post operative sore throat. Patients will be nebulized 30 minutes before intubation in pre operative area and will be assessed post operatively for any complaints of throat pain, hoarseness and cough at 0, 4, 8, 12 & 24 hours.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2019-12-19
• Study Start: 2019-12-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

(1) Patient willing to participate (2) Patient of ASA 1 & 2 physical status (3) Patient between 18-55 years of age of either sex (4) Patient with mallampati score 1 & 2.

Exclusion Criteria

(1) Patient refusal to participate, (2) Patient with ASA physical status 3 and above (3) Patient aged less than 18 years and more than 55 years (4) Patient with suspected difficult airway and mallampati grade 3 & 4 (5) Patient with pregnancy,morbid obesity,h/o sore throat (6) Patient with failed intubation in two times.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of nebulized dexamethasone with that of magnesium sulphate in decreasing the incidence and severity of post operative sore throat.	Incidence of post operative throat pain,hoarseness and cough will be assessed at 0hr,4hr,8hr,12hr and 24hr.

Secondary Outcome Measures

Name	Time	Method
Adverse effects of dexamethasone and magnesium sulphate, if any	Upon discharge patient will be instructed to report when symptom appear

Trial Locations

Locations (1)

Indira Gandhi Institute of Medical Sciences Patna; 🇮🇳 Patna, BIHAR, India

Indira Gandhi Institute of Medical Sciences Patna

🇮🇳Patna, BIHAR, India

SHWETA BHARTI HEMBROM

Principal investigator

7739132922

ketyshweta@gmail.com