A comparative study of pre-operative dexamethasone nebulization and magnesium sulphate nebulization in incidence and severity of post operative sore throat.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- To compare the efficacy of nebulized dexamethasone with that of magnesium sulphate in decreasing the incidence and severity of post operative sore throat.
研究概览
简要总结
Post operative sore throat is one of the common complication of laryngoscopy and endotracheal intubation. Different agents like lignocaine jelly, ketamine gargles, iv dexamethasone, magnesium sulphate gargles & lozenges have been used with variable success in decreasing the incidence and severity of post operative sore throat. This is a comparativetudy to see the effects of nebulization dexamethasone and magnesium sulphate in incidence and severity of post operative sore throat. Patients will be nebulized 30 minutes before intubation in pre operative area and will be assessed post operatively for any complaints of throat pain, hoarseness and cough at 0, 4, 8, 12 & 24 hours.
研究设计
- 研究类型
- Interventional
- 分配方式
- Random Number Table
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •(1) Patient willing to participate (2) Patient of ASA 1 & 2 physical status (3) Patient between 18-55 years of age of either sex (4) Patient with mallampati score 1 & 2.
排除标准
- •(1) Patient refusal to participate, (2) Patient with ASA physical status 3 and above (3) Patient aged less than 18 years and more than 55 years (4) Patient with suspected difficult airway and mallampati grade 3 & 4 (5) Patient with pregnancy,morbid obesity,h/o sore throat (6) Patient with failed intubation in two times.
结局指标
主要结局
To compare the efficacy of nebulized dexamethasone with that of magnesium sulphate in decreasing the incidence and severity of post operative sore throat.
时间窗: Incidence of post operative throat pain,hoarseness and cough will be assessed at 0hr,4hr,8hr,12hr and 24hr.
次要结局
- Adverse effects of dexamethasone and magnesium sulphate, if any(Upon discharge patient will be instructed to report when symptom appear)