Respiratory Oscillometry for the Prediction of Bronchopulmonary Dysplasia
- Conditions
- Bronchopulmonary Dysplasia
- Registration Number
- NCT05986032
- Lead Sponsor
- Fondazione IRCCS San Gerardo dei Tintori
- Brief Summary
The goal of this observational study is to learn about the correlation between respiratory system reactance, as assessed by respiratory oscillometry, and respiratory outcomes in preterm infants born before 32 weeks of gestation. The main question it aims to answer is if the reactance z-score at 7 postnatal days adds to relevant clinical factors in the prediction of bronchopulmonary dysplasia. Participants will receive respiratory oscillometry measurements at 7 ± 2 postnatal days.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 150
- born before 32 weeks post-menstrual age
- congenital abnormalities
- Inherited disorders of metabolism
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Respiratory system reactance (Xrs) at the clinical positive end-expiratory pressure Xrs will be measured at 7 days of life Xrs will be expressed in z-score using reference equation for very preterm infants
- Secondary Outcome Measures
Name Time Method Respiratory system reactance (Xrs) at the clinical positive end-expiratory pressure and ± 2 cmH2O Xrs will be measured at 7 days of life Xrs will be expressed in cmH2O\*S/L
Trial Locations
- Locations (6)
Medical University of Vienna
🇦🇹Vienna, Wien, Austria
Fondazione IRCCS San Gerardo dei Tintori
🇮🇹Monza, Monza E Brianza, Italy
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
🇮🇹Milano, Italy
Amsterdam UMC
🇳🇱Amsterdam, Netherlands
Uppsala University Children's Hospital
🇸🇪Uppsala, Sweden
Universitäts-Kinderspital beider Basel
🇨🇭Basel, Switzerland
Medical University of Vienna🇦🇹Vienna, Wien, Austria