EUROvitalis Plus: cognitive training effects of a neuropsychological program in combination with a physical training and nutrition educatio

Not Applicable

Recruiting

Conditions: healthy older adults, healthy cognitive aging

Registration Number: DRKS00005194

Lead Sponsor: niversität Vechta, Institut für Gerontologie und Center für Neuropsychologische Diagnostik und Intervention

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 72

Inclusion Criteria

cognitive healthy elderly of all educational backgrounds and sufficient verbal skills in German

Exclusion Criteria

at T0: when participant suffers a neurological or psychiatric disease or alcohol or drug abuse or when vision, hearing or speech is impaired or the achieved score is < 13 in DemTect or > 19 in BDI-II; exclusion of statistical analysis if < 11 sessions (11 sessions match ca. 80% of attendance time) are visited

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvements in cognitive subdomains: attention (Brief test of attention); memory (DemTect, Subtests word list and delayed recall; Complex-Figure-Test); visuo-construction (Complex-Figure-Test); working memory (DemTect, Subtest digit span backwards); word fluency (DemTect, Subtest supermarket/animals; Regensburger Wortflüssigkeits-Test , different subtests); processing speed (Trail Making Test-A; Stroop Test); executive functions (Trail Making Test-B; Stroop Test; BADS, Subtests Key Search, Zoo Map and DEX), and in overall cognitive function (DemTect). The primary outcome will be assessed at times T0 (pretest), T1 (posttest after the intervention), T2 (follow-up after one year), T3 (follow-up after two years).

Secondary Outcome Measures

Name	Time	Method
Improvements in<br>1. neurophysiological parameters: assessment of the APO-E- and the BDNF-Genotype, assessment of the level of BDNF, IGF-1, VEGF in the blood.<br>2. non-cognitive domains: quality of life (WHOQOL-BREF), physical fitness (Senior Fitness Test), motivational questionnaires, questionnaire about nutrition.<br>All secondary outcomes will be assessed at times T0 (pretest) and T1 (posttest after the intervention). At T2 (follow-up after one year) and T3 (follow-up after two years) alone the cognitive subdomains will be assessed.