balanced salt solution versus normal saline in resuscitation of pediatric sepsis: A double-blinded randomized control trial

Not Applicable

Recruiting

• Conditions: metabolic acidosishyperchloremic metabolic acidosislactate clearancerenal injurycoagulopathylength of stay; balanced salt solution; pediatric sepsis; septic shock; shock; fluid; normal saline; renal injury; fluid- related complication

• Registration Number: TCTR20170605001
• Lead Sponsor: Ratchadapiseksomphot Fund, Faculty of Medicine, Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-06-05
• Study Completion: 2018-06-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

pediatric patients diagnosed as septic shock, requiring fluid bolus therapy

Exclusion Criteria

pre-existing renal failure
uncontrolled liver failure

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
acid-base status 2 hr, 6 hr, 24 hr lactate clearance, blood pH, base excess

Secondary Outcome Measures

Name	Time	Method
fluid-related complications 2 hr, 6 hr, 24 hr, 48 hr, 72 hr, 96 hr renal injury (urinary neutrophil gelatinase-associated lipocalin, creatinine, renal replacement ther