Gene Expression (GE) and MicroRNA (MIRNA) Expression Profiles of Malignant Rhabdoid Tumors (MRT) of the Kidney (RTK) and Atypical Teratoid Rhabdoid Tumor (ATRT)
Trial Snapshot
- Phase
- Not Applicable
- Status
- Withdrawn
- Sponsor
- Children's Oncology Group
- Locations
- 1
- Primary Endpoint
- Molecular differences between RTK and the ATRT
Study Overview
Brief Summary
This research trial studies biomarkers in samples from patients with rhabdoid tumor of the kidney and atypical teratoid rhabdoid tumor. Studying biomarkers of tissue samples from patients with cancer in the laboratory may help doctors learn more about changes the occur in DNA and identify biomarkers related to cancer.
Detailed Description
PRIMARY OBJECTIVES:
I. To determine if there are molecular differences between rhabdoid tumor of the kidney (RTK) and the atypical teratoid rhabdoid tumor (ATRT).
OUTLINE:
Archived tumor tissue samples are analyzed for gene expression profile and microRNA profile.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Samples of RTK and ATRT provided by the Children?s Oncology Group (COG)
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Molecular differences between RTK and the ATRT
Time Frame: Up to 3 months
Secondary Outcomes
No secondary outcomes reported
