Erector Spinae vs. PENG Block for Total Hip Arthroplasty

Phase 4

Completed

• Conditions: Hip Pain Chronic; Hip Arthropathy; Hip Osteoarthritis
• Interventions: Drug: Ropivacaine 0.2% Injectable Solution Erector Spinae Plane Block; Drug: Control Test; Drug: Ropivacaine 0.2% Injectable Solution - PENG block

• Registration Number: NCT06083428
• Lead Sponsor: Poznan University of Medical Sciences

Brief Summary

Effect of PENG block and ESPB on pain management, and NLR and PLR following knee arthroplasty

Detailed Description

Hip arthroplasty is one of the most common orthopedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prosthesis. Regional anesthesia methods may be performed to reduce the inflammatory response, opioid consumption, and opioid-related side effects.

In recent years, the influence of regional anesthesiology on reducing the inflammatory response after surgical procedures has been emphasized. However, very few studies have evaluated the effect of various methods of anesthesia on the NLR.

This is the first study to investigate the effect of regional anesthesia on the NLR and PLR in patients undergoing hip replacement surgery.

Study Timeline

• Study First Submitted: 2023-05-24
• Study First Submitted QC: 2023-10-11
• Study First Posted: 2023-10-16
• Study Start: 2023-10-17
• Status Verified: 2024-06
• Primary Completion: 2024-06-11
• Study Completion: 2024-06-11
• Last Update Submitted: 2024-06-17
• Last Update Posted: 2024-06-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Patients with ASA classification I-III, Aged 20-90 years, Who will be scheduled for hip arthroplasty under spinal anesthesia.

Exclusion Criteria

• Patients who have a history of bleeding diathesis, Take anticoagulant therapy, have a History of chronic pain before surgery, have Multiple trauma, cannot assess their pain (dementia), have been operated on under general anesthesia, have an infection in the area and do not accept the procedure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
ESPB group	Ropivacaine 0.2% Injectable Solution Erector Spinae Plane Block	ultrasound guided erector spinae plane block - 20ml 0,2% ropivacaine
Control group	Control Test	Only spinal anesthesia - No peripheral nerve block
PENG Block group	Ropivacaine 0.2% Injectable Solution - PENG block	ultrasound guided PENG block - 20ml 0,2% ropivacaine

Primary Outcome Measures

Name	Time	Method
Opioid consumption	48 hours after surgery	Total opiate consumption after surgery

Secondary Outcome Measures

Name	Time	Method
first need of opiate	48 hours after procedure	Time after surgery when the patient needs opiate for the first time
Neutrophil-to-lymphocyte ratio	48 hours after surgery	Neutrophil-to-lymphocyte ratio
Quadriceps muscle strength assessed using medical research council scale [range 0:5]	Postoperative 24 hours period	Quadriceps muscle strength (knee extension and hip adduction) will be evaluated according to the medical research council muscle strength rating
Numerical Rating Scale [range 0:10]	48 hours after surgery	Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt)
Platelet-to-lymphocyte ratio	48 hours after surgery	Platelet-to-lymphocyte ratio

Trial Locations

Locations (1)

Poznan University of Medical Sciences; 🇵🇱 Poznan, Poznań, Poland