Erector Spinae Plane Block (ESPB) vs. PENG Block for Pain Management and Stress Response in Patients Undergoing Total Hip Arthroplasty. A Prospective, Randomized Trial.
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Opioid consumption
研究概览
简要总结
Effect of PENG block and ESPB on pain management, and NLR and PLR following knee arthroplasty
详细描述
Hip arthroplasty is one of the most common orthopedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prosthesis. Regional anesthesia methods may be performed to reduce the inflammatory response, opioid consumption, and opioid-related side effects.
In recent years, the influence of regional anesthesiology on reducing the inflammatory response after surgical procedures has been emphasized. However, very few studies have evaluated the effect of various methods of anesthesia on the NLR.
This is the first study to investigate the effect of regional anesthesia on the NLR and PLR in patients undergoing hip replacement surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with ASA classification I-III, Aged 20-90 years, Who will be scheduled for hip arthroplasty under spinal anesthesia.
排除标准
- •Patients who have a history of bleeding diathesis, Take anticoagulant therapy, have a History of chronic pain before surgery, have Multiple trauma, cannot assess their pain (dementia), have been operated on under general anesthesia, have an infection in the area and do not accept the procedure
研究组 & 干预措施
PENG Block group
ultrasound guided PENG block - 20ml 0,2% ropivacaine
干预措施: Ropivacaine 0.2% Injectable Solution - PENG block (Drug)
ESPB group
ultrasound guided erector spinae plane block - 20ml 0,2% ropivacaine
干预措施: Ropivacaine 0.2% Injectable Solution Erector Spinae Plane Block (Drug)
Control group
Only spinal anesthesia - No peripheral nerve block
干预措施: Control Test (Drug)
结局指标
主要结局
Opioid consumption
时间窗: 48 hours after surgery
Total opiate consumption after surgery
次要结局
- first need of opiate(48 hours after procedure)
- Neutrophil-to-lymphocyte ratio(48 hours after surgery)
- Quadriceps muscle strength assessed using medical research council scale [range 0:5](Postoperative 24 hours period)
- Numerical Rating Scale [range 0:10](48 hours after surgery)
- Platelet-to-lymphocyte ratio(48 hours after surgery)