A study on the efficacy of the drug Dexamethasone in the prevention of noisy breathing after extubation.
Phase 4
- Conditions
- Health Condition 1: J384- Edema of larynx
- Registration Number
- CTRI/2019/12/022511
- Lead Sponsor
- All India Institute of Medical sciences Raipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Children admitted in the PICU and requiring airway stabilization and mechanical ventilation.
2. Duration of intubation more than 24 hours and not exceeding 14 days.
Exclusion Criteria
1). Vocal cord anomalies and other anatomic abnormalities of the upper airways beforeintubation
2). Previous use of corticosteroids during hospitalization within the past 7 days.
3). Clinical contraindication for the use of corticosteroids.
4).Surgical trauma to the upper airway.
5).A history of previous upper airway obstruction
( subglottic stenosis)
6). Patients with pseudobulbarpalsy
7). Spontaneous extubation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Stridor score more than or equal to 4 requiring intubationTimepoint: 0 6 12 24 48 hours
- Secondary Outcome Measures
Name Time Method CLR MTV SOFA scoreTimepoint: 0 6 12 24 48 hours