Exercise Intervention on Conflict Monitoring in Children With Attention-deficit Hyperactivity Disorder

Not Applicable

Completed

• Conditions: Exercise Intervention
• Interventions: Other: High-intensity interval training

• Registration Number: NCT04112758
• Lead Sponsor: National Taiwan Normal University

Brief Summary

The study mainly investigates the effect of high-intensity interval training on conflict monitoring in children with ADHD by using event-related potential and sLORETA techniques.

Detailed Description

The present study will have two experiments, one is a cross-section study and the other is intervention study.

As for cross-section study, typical developmental children and children with ADHD will perform the stroop task while recording their brain waves.

The intervention is twice a week for 5 weeks and before and after the intervention, children with ADHD will randomly assign to either an exercise group or control group. They will perform the stroop task while recording their brain waves.

Study Timeline

• Study First Submitted: 2019-09-27
• Study First Submitted QC: 2019-09-30
• Study First Posted: 2019-10-02
• Study Start: 2020-06-01
• Primary Completion: 2021-04-30
• Study Completion: 2022-01-23
• Status Verified: 2023-01
• Last Update Submitted: 2023-01-14
• Last Update Posted: 2023-01-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

1. age between 7 and 12 years
2. diagnosed with ADHD by a pediatric psychiatrist, which is not required for TD
3. no history of brain injury or neurological conditions, such as exhibited epileptic seizures, serious head injuries, and periods of unconsciousness.

Exclusion Criteria

1. cannot follow the instruction
2. cannot complete all the procedure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Exercise group	High-intensity interval training	The group will receive twice a week for 5 week

Primary Outcome Measures

Name	Time	Method
Behavioral performance	Day 0 and post-intervention at Week 5	response accuracy (percentage) is generated by computerized task defined as percentage of trials that successfully responded to target stimulus

Secondary Outcome Measures

Name	Time	Method
N2 & P3 components	Day 0 and post-intervention at Week 5	Electroencephalographic (EEG) activity will be measured at 64 sites. The amplitude of the N2 is defined as the mean amplitude within a 50-ms interval surrounding the maximal negative peak within a 200- to 400-ms latency window.; The amplitude of the P3 is defined as the mean amplitude within a 50-ms interval surrounding the maximal positive peak within a 300- to 800-ms latency window.

Trial Locations

Locations (1)

National Taiwan Normal University; 🇨🇳 Taipei, Taiwan