Immune Responses in Mothers of Term and Preterm Low-Birth-Weight: Levels of CD4+ and CD8+ T Cells in Gingival Granulation Tissue

Phase 1

Completed

• Conditions: Preterm low birth weight; deliver preterm low- birth- weight, periodontitis, CD4, CD8

• Registration Number: TCTR20190407001
• Lead Sponsor: Selcuk University, BAP

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2010-10-03
• Study Start: 2019-04-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 67

Inclusion Criteria

Presence of at least 20 teeth in their mouth and at least two teeth with >5mm probing depth and clinical attachment loss; no history of initial periodontal therapy including scaling and root planing at least six weeks prior to the study.

Exclusion Criteria

Women presenting risk factors to preterm/low-birth-weight: history of diseases including diabetes mellitus, genitourinary tract infections or HIV infection, previous multiple gestations, previous preterm birth/low-birth-weight infants, in vitro fertilization procedures, placental or cervical or uterine abnormalities, history of infertility, history of illegal drug use, history of human immunodefficiency virus type I or hemoglobin levels less than 8 mg/dl following delivery and medical conditions that required antibiotics prophylaxis.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
CD4+ and CD8+ T lymphocytes in gingival tissue mohter with preterm low-birth-weight infants 24 Hours square micrometer

Secondary Outcome Measures

Name	Time	Method
CD4+ and CD8+ T lymphocytes with periodontitis patient 24 Hours square micrometer