Effect of animal and plant proteins on glycaemic response to staple carbohydrates

Not Applicable

Completed

• Conditions: Diabetes; Metabolic disorder; Metabolic and Endocrine - Metabolic disorders; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12619000777190
• Lead Sponsor: ew Zealand Institute for Plant & Food Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-05-24
• Study Completion: 2019-12-13
• Last Update Posted: 27 July 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

•Age: Aged between 18 and 65.
•Sex: Male or female.
•Glucose tolerance: No history of diabetes or evidence of glucose intolerance in a preliminary screening test.
•Tolerant to potato, pasta, rice, meat and plant protein.
•Health: Healthy as gauged by self-assessment and result on the General Health Questionnaire.
•Agreement: Subject having given written informed consent to comply with the conditions of the trial.

Exclusion Criteria

•Glucose intolerance: Any history of diabetes or evidence of glucose intolerance in a preliminary test less than 6.0mmol/l fasting glucose, International Diabetes Federation recommendation) and HbA1c greater than 40 mmol/mol
•Non-fasting: Having consumed anything apart from water in the twelve hours prior to the test.
•Vegetarian or vegan
•Allergic or intolerant to potatoes, pasta, rice, plant protein and meat
•Pregnant or breastfeeding.
•Long term chronic illnesses requiring treatment, such as cancer and cardiovascular disease.
•Gut conditions or drugs effecting gut transit time, such as irritable bowel syndrome, peptic ulcers and laxatives.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine the effect of lamb and plant protein on the glycaemic responses to potato, pasta and rice. [Measure blood glucose concentrations at baseline (time 0 minute), 15, 30, 45, 60, 90, 120 and 150 minutes after a serving of the test meal (equivalent 40 g carbohydrate). Nine test sessions will be conducted with at least a 48-hour washout between sessions. <br>Primary timepoint is the baseline which is time zero (0 minute).]

Secondary Outcome Measures

Name	Time	Method
To determine the effect of lamb and plant protein on the insulin responses to potato, pasta and rice.[Measure insulin concentrations at 0, 15, 30, 45, 60, 90, 120 and 150 minutes after a serving of the test meal (equivalent 40 g carbohydrate). Nine test sessions will be conducted with at least a 48-hour washout between sessions.];Measure satiety with a visual analogue scale following consumption of the test meal[A visual analogue scale will be used to measure appetite over the 2.5 hours at 0, 30, 60, 120 and 150 mins. Nine test sessions will be conducted with at least a 48-hour washout between sessions. ]