Incidence of pruritus after administration of intrathecal Fentanyl in orthopaedic surgeries.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 85
- 试验地点
- 1
- 主要终点
- Incidence of pruritus
研究概览
简要总结
Patients to be posted for lower limb orthopaedic surgeries under spinal anaesthesia will be included in the study. After informed consent, spinal anaesthesia will be given in L3-4 intervertebral space in sitting position. Hyperbaric Bupivacaine (10 - 15 mg) and Fentanyl (25 mcg) will be injected intrathecally.
After administration of intrathecal fentanyl, occurence and severity of pruritus will be assessed. Severity of pruritus will be scored from 0-2 (where 0 = no pruritus, 1 = mild to moderate pruritus requiring no treatment, 2 = severe pruritus requiring treatment) at 30 min, 1 hour, 2 hour, 4 hour and 6 hour. Site of pruritus will also be documented.
In case of severe pruritus, Inj. Nalbuphine 2 - 3 mg will be given IV. If no response then Inj. Naloxone 0.1 - 0.2 mg will be given.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients receiving spinal anaesthesia using local anaesthetics & Fentanyl for lower limb orthopaedic surgeries.
排除标准
- •Patients having skin disease with pruritus 2)Patients having systemic disease with pruritus 3)Patient receiving antihistaminics or steroids 4)Patients with Opioid dependency 5)Patients with Psychiatric disorders.
结局指标
主要结局
Incidence of pruritus
时间窗: Intraoperative and postoperative for 6 hours
次要结局
- severity of pruritus(at 30 min., 1 hour, 2 hour, 4 hour and 6 hour after administration of intrathecal fentanyl)