NL-OMON42933
Completed
Not Applicable
Pilot study: Biomarkers for the diagnosis of severe neutrophil inflammatory asthma. - Biomarkers for severe neutrophil inflammatory asthma
Rijnstate Ziekenhuis0 sites40 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Rijnstate Ziekenhuis
- Enrollment
- 40
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All patients included in this study suffer from severe asthma. When a diagnosis of asthma is confirmed and comorbidities have been addressed, severe asthma is defined as asthma which requires treatment with high dose inhaled corticosteroids (ICS) plus a second controller (and/or systemic CS) to prevent it from becoming \*uncontrolled\* or which remains \*uncontrolled\* despite this therapy.
Exclusion Criteria
- •\-People suffering from other (chronic, pulmonary or autoimmune) diseases than asthma
- •\-People suffering from an upper or lower respiratory infection within four weeks prior to investigation
- •\-People having an immunodeficiency
- •\-People taking antibiotics (macrolide trial included) or probiotics, four weeks prior to investigation
- •\-People taking oral corticosteroids
- •\-People who smoke.
Outcomes
Primary Outcomes
Not specified
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