A Comparative Study of Three Airway Clearance Techniques With Different Autonomy Degrees in Non Cystic Fibrosis Bronchiectasis: Randomized Cross-over Trial.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Bronchiectasis
- Sponsor
- Hospital Clinic of Barcelona
- Enrollment
- 31
- Locations
- 1
- Primary Endpoint
- Weight of sputum expectorated during each airway clearance therapy session
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
Study design: a randomized, crossover trial. Each patient performed three different airway clearance techniques (Autogenic drainage, slow expiratory with glottis opened in lateral posture [ELTGOL], temporary- positive expiratory pressure [T-PEP] with not similar autonomy degree in a randomized order. Each technique were applied in 3 sessions during one week at alternate days (Monday /Wednesday/Friday or Tuesday/Thursday/Saturday). The time spent in each bronchial session was 40 minutes. Seven days were the wash-out time period between the different techniques.
Investigators
Beatriz Herrero
Physiotherapist
Hospital Clinic of Barcelona
Eligibility Criteria
Inclusion Criteria
- •Non Cystic Fibrosis bronchiectasis diagnosed by High Resolution Computed Tomographic
- •Mean sputum production ≥ 15 ml /24h
- •Clinical stability in the last 6 weeks
- •Not carrying out regular chest physiotherapy
- •Forced expiratory volume in 1 second ≥ 30% pred. ; Forced Vital Capacity ≥ 45% pred. and peak expiratory flow \>270 L/s
Exclusion Criteria
- •Smoker or non-smoker form less than 2 years
- •Cystic fibrosis
- •Active tuberculosis or sarcoidosis
Outcomes
Primary Outcomes
Weight of sputum expectorated during each airway clearance therapy session
Time Frame: 40 minutes
Wet weight sputum production were recollected in one pre-weighted containers. It was measured in grams.
Weight of sputum expectorated 24 hours post each bronchial session
Time Frame: 24 hours
Wet weight sputum production were recollected in one pre-weighted containers. It was measured in grams.
Secondary Outcomes
- Saint George Respiratory Questionnaire (SGRQ)(Change from baseline at 5 weeks)
- Leicester Cough Questionnaire (LCQ)(Changes from baseline arm to 1 week)