CTRI/2021/07/035065
Not yet recruiting
未知
Isotonic bicarbonate vs. Balanced Salt Solution as resuscitation fluid in patients with severe metabolic acidosis: a randomized control trial
AIIMS new delhi0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems
- Sponsor
- AIIMS new delhi
- Status
- Not yet recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •i) 18 years of age or above, ii) pH \<\= 7\.2 and iii) bicarbonate \<\=20 meq/liter, iv) Baseline Sequential Organ Failure (SOFA) score \>\=2, v) lactate \>\= 2 mmol/litre requiring fluid resuscitation
Exclusion Criteria
- •PaCO2 \>\=45 mm Hg, known chronic kidney disease (CKD) stage \>\=IV or congestive cardiac failure (CHF) with hypervolemia (as seen on ultrasound and echocardiography), pregnant, already on some form of bicarbonate therapy, unknown poisoning with suspected external acid ingestion.
- •Study design : Prospective randomized control trail (RCT)
Outcomes
Primary Outcomes
Not specified
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