ongterm effects of severe infections and sepsis.
- Conditions
- infection, sepsis, mitochondrial dysfunction
- Registration Number
- NL-OMON21743
- Lead Sponsor
- niversity Medical Center Groningen
- Brief Summary
https://www.ncbi.nlm.nih.gov/pubmed/29905628
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Adult patients, aged between 18 and 85 years
-Able to provide (deferred) informed consent themselves or informed consent can be obtained via next of kin or legal guardian
Exclusion Criteria
A potential subject who meets any of the following criteria will be excluded from participation in this study:
- Discharged home without hospital admittance after ED visit
- Congenital mitochondrial diseases
- Renal transplant recipients
- Hepatic failure (Child Pugh C)
- Hepatorenal syndrome
- Start of antibiotics before blood sampling
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective of the current project is to study the association between biomarkers for renal mitochondrial damage in sepsis with the change in renal function and mortality after sepsis.
- Secondary Outcome Measures
Name Time Method