Comparison of drug Methotrexate against drugs Methotrexate with Apremilast in Psoriasis disorder
Not Applicable
- Conditions
- Health Condition 1: L400- Psoriasis vulgaris
- Registration Number
- CTRI/2022/01/039825
- Lead Sponsor
- GMERS Medical College and CIvil Hospital Sola
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients ready to be part of study and sign ICF.
2. Patient presenting with Moderate to Severe Chronic Plaque Psoriasis according to the Rule of Tens (PASI score >10)
Exclusion Criteria
1. Patients who failed to give written consent.
2. In patients in which Methotrexate and/or Apremilast is contraindicated
3. Pregnant women and Lactating Mothers
4. Patients with mild disease (PASI <10)
5. Erythrodermic or pustular psoriasis, predominant scalp or nail involvement
6. Patients who have taken methotrexate continuously or intermittently in more than 2.5gm total dose.
7. Patients with hepatic or renal impairment, cardiac dysfunction, blood dyscrasias or any other systemic comorbidity.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method