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临床试验/NCT02583750
NCT02583750已完成不适用

Snooze Control: The Effect of Sleep Deprivation on Glucose Metabolism

Xuewen Wang2 个研究点 分布在 1 个国家目标入组 16 人开始时间: 2014年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
16
试验地点
2
主要终点
Glucose concentrations during oral glucose tolerance test

研究概览

简要总结

This project investigated how glucose metabolism differs due to sleep deprivation for three consecutive nights as compared to sufficient sleep for three nights by examining concentrations of glucose, insulin, and other factors involved in glucose metabolism.

详细描述

16 participants were enrolled in the study (8 females, 8 males) aged 18-25 years. In order for the participants to qualify for the study, each had to wear a pedometer for a week before the study began to determine eligibility. Each participant came to the lab for an oral glucose tolerance test on a morning, following three nights when they were sleep deprived, and on another morning when they had three nights' sufficient sleep. The sequence of the oral glucose tolerance tests were randomly assigned. The sleep duration for participants was monitored by the readings of the sleep monitors that each participant wore. The oral glucose tolerance tests were performed after an overnight fast. A 20-gauge polyethylene catheter was placed in the antecubital vein for blood sampling. Blood samples were drawn once (0 min) before and 4 times (30, 60, 90, and 120 min) after a 75g glucose drink was consumed for the determination of plasma glucose, insulin, and concentrations of other factors. Each participant was told to continue their regular routine during the study period, including diet, caffeine usage, and exercise.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Crossover
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
18 Years 至 25 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • healthy college-aged males and females
  • being minimally active

排除标准

  • average more than 15,000 steps a day
  • major health issues such as heart disease, diabetes
  • taking medication to help with sleep or using a sleeping device
  • any type of sleep problem such as sleep apnea

结局指标

主要结局

Glucose concentrations during oral glucose tolerance test

时间窗: two hours

次要结局

未报告次要终点

研究者

发起方
Xuewen Wang
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Xuewen Wang

Dr. Xuewen Wang, PhD.

University of South Carolina

研究点 (2)

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Snooze Control: Sleep Duration & Glucose Metabolism | 临床试验