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Clinical Trials/NCT02583750
NCT02583750
Completed
Not Applicable

Snooze Control: The Effect of Sleep Deprivation on Glucose Metabolism

Xuewen Wang1 site in 1 country16 target enrollmentJanuary 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Glucose Metabolism Disorders
Sponsor
Xuewen Wang
Enrollment
16
Locations
1
Primary Endpoint
Glucose concentrations during oral glucose tolerance test
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

This project investigated how glucose metabolism differs due to sleep deprivation for three consecutive nights as compared to sufficient sleep for three nights by examining concentrations of glucose, insulin, and other factors involved in glucose metabolism.

Detailed Description

16 participants were enrolled in the study (8 females, 8 males) aged 18-25 years. In order for the participants to qualify for the study, each had to wear a pedometer for a week before the study began to determine eligibility. Each participant came to the lab for an oral glucose tolerance test on a morning, following three nights when they were sleep deprived, and on another morning when they had three nights' sufficient sleep. The sequence of the oral glucose tolerance tests were randomly assigned. The sleep duration for participants was monitored by the readings of the sleep monitors that each participant wore. The oral glucose tolerance tests were performed after an overnight fast. A 20-gauge polyethylene catheter was placed in the antecubital vein for blood sampling. Blood samples were drawn once (0 min) before and 4 times (30, 60, 90, and 120 min) after a 75g glucose drink was consumed for the determination of plasma glucose, insulin, and concentrations of other factors. Each participant was told to continue their regular routine during the study period, including diet, caffeine usage, and exercise.

Registry
clinicaltrials.gov
Start Date
January 2014
End Date
September 2014
Last Updated
10 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Xuewen Wang
Responsible Party
Sponsor Investigator
Principal Investigator

Xuewen Wang

Dr. Xuewen Wang, PhD.

University of South Carolina

Eligibility Criteria

Inclusion Criteria

  • healthy college-aged males and females
  • being minimally active

Exclusion Criteria

  • average more than 15,000 steps a day
  • major health issues such as heart disease, diabetes
  • taking medication to help with sleep or using a sleeping device
  • any type of sleep problem such as sleep apnea

Outcomes

Primary Outcomes

Glucose concentrations during oral glucose tolerance test

Time Frame: two hours

Study Sites (1)

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