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临床试验/CTRI/2025/11/098188
CTRI/2025/11/098188尚未招募2 期

EFFECT OF HIGH-INTENSITY INTERVAL TRAINING (HIIT) IN PREMENSTRUAL DYSPHORIC DISORDER (PMDD): AN EXPERIMENTAL STUDY

Sanjeevani Konda1 个研究点 分布在 1 个国家目标入组 35 人开始时间: 2025年12月25日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
35
试验地点
1
主要终点
Daily Record of Severity of Problems (DRSP)

研究概览

简要总结

Title:Effect of High-Intensity Interval Training (HIIT) in Premenstrual Dysphoric Disorder (PMDD): An Experimental StudyPremenstrual Dysphoric Disorder (PMDD) is a severe form of premenstrual syndrome characterized by physical, emotional, and behavioral symptoms that significantly impair daily life. Current pharmacological treatments, such as SSRIs and hormonal therapies, though effective, often have side effects and limitations, creating the need for safe, non-pharmacological alternatives. This study aims to evaluate the effect of a 4-week High-Intensity Interval Training (HIIT) program on PMDD symptoms in women aged 18–25 years. The intervention involves progressively structured HIIT sessions focusing on cardiovascular and strength exercises, delivered five times per week for 30 minutes each session. Outcomes will be assessed using the Daily Record of Severity of Problems (DRSP) for symptom monitoring, C-Reactive Protein (CRP) levels as a biomarker of inflammation, and the Visual Analogue Scale (VAS) for subjective symptom intensity. A quasi-experimental design with 35 participants will be employed, and statistical analysis will include paired t-tests and non-parametric tests where applicable. This study intends to explore whether HIIT can reduce systemic inflammation and symptom severity in PMDD, thereby providing a cost-effective, drug-free, and holistic management strategy to improve the quality of life in affected women.

研究设计

研究类型
Interventional
分配方式
Other
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 25.00 Year(s)(—)
性别
Female

入选标准

  • Females diagnosed with Premenstrual Dysphoric Disorder (PMDD), based on clinical criteria DRSP.

排除标准

  • Females on hormonal medication Individuals with other comorbid conditions like musculoskeletal injuries, obesity, and neurological conditions.
  • Any inflammatory conditions.
  • Red flags of HIIT include anemia or low BP, pelvic floor dysfunction, pre-diagnosed depression or other psychological issues, hypermobility, or ligament laxity.

结局指标

主要结局

Daily Record of Severity of Problems (DRSP)

时间窗: 2 months

次要结局

  • Visual Analogue Scale (VAS)(2 mins)
  • C-Reactive Protein (CRP) Levels(60 mins)

研究者

发起方
Sanjeevani Konda
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Sanjeevani Konda

KLE Institute of Physiotherapy

研究点 (1)

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